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Arsenal’s defensive injury crisis worsened as Shkodran Mustafi limped off in the second half of their game against Huddersfield at the Emirates.
The German centre-back pulled up with a hamstring problem just after the hour mark and immediately signalled to the bench to be replaced.
He limped off the field and Nacho Monreal , himself working has way back from injury problems, came on to make his first appearance since October.
Unai Emery will now be sweating over the fitness of Mustafi ahead of a hectic festive period after losing first choice centre-back Rob Holding to a long-term knee injury on Wednesday
Holding was stretchered off in their 2-2 draw with Manchester United at Old Trafford and further tests revealed a ruptured anterior cruciate ligament which will keep him out for up to nine months.
Laurent Koscielny, working his way back to fitness since suffering an achilles injury in May, was on the bench for the first time since his lay-off.
But the decision to bring on Monreal rather than Koscielny suggests he is still not fit enough for first-team action and their situation is looking increasingly bleak at the back
Monreal was the final substitution for Arsenal after Emery made a double switch at half-time in an attempt to break down the resilient Terriers.
He took off Alexandre Lacazette and Stephan Lichtsteiner to introduce a more attacking formation with Alex Iwobi and Henrikh Mkhitaryan brought on for the second half.